Abundance of Prevotella in the gut microbiota is associated with reduced allergy – data from other studies


In a study of 233 children (mean age 6 years) with IgE-mediated food allergy and 58 age-matched controls, Prevotella was the most overrepresented species in non-allergic controls, and there was evidence of Prevotella copri abundance being lowest in children with peanut allergy.

Microbial signature in IgE-mediated food allergies. Goldberg MR, et al. Genome Med. 2020 Oct 27;12(1):92.


In this study the gut microbiome in 36 young children with atopic dermatitis and 47 controls were compared. The abundance of Prevotella was significantly increased in the stool samples of the control children.

Effects of diet on the childhood gut microbiome and its implications for atopic dermatitis.  Mahdavinia M, at al. J Allergy Clin Immunol. 2019 Apr;143(4):1636-1637.


The gut microbiome from 21 children with IgE-mediated allergic disease and 72 controls was assessed at 6 months, 13 months, and 8 years. The abundance of Prevotella was underrepresented in allergic children at all time points.

Temporal and long-term gut microbiota variation in allergic disease: A prospective study from infancy to school age.  Simonyté Sjödin K, et al. Allergy. 2019 Jan;74(1):176-185.